Ceftriaxone is indicated for the treatment of the following major infections:
Lower respiratory tract infections
Acute Bacterial Otitis Media
Skin and skin structure infections
Urinary tract infections
Gonorrhea
Bacterial Septicemia
Bone and joint infections
Meningitis
Prevention of postoperative infections
Perioperative prophylaxis of infections associated with surgery
Dosage & Administration:
Adult: The usual dose is 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day).
Pneumonia, Bronchitis, Acute bacterial otitis media, Skin and skin structure infection, Urinary tract infections, Bacterial Septicemia, Bone and joint infections, Meningitis: 1 to 2 g IV or IM once a day (or in equally divided doses twice a day); Maximum dose: 4 gm/day
Uncomplicated gonococcal infections: 250 mg IM as a single dose
Surgical prophylaxis: 1 g IV as a single dose 30 to 120 minutes before surgery
Infants and Children (01 month or older): The usual dose is 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day).
Pneumonia, Bronchitis, Skin and skin structure infection, Urinary tract infections, Bacterial Septicemia, Bone and joint infections: 50 to 75 mg/kg IV or IM once a day (or in equally divided doses twice a day); Maximum dose: 2 gm/day
Acute bacterial otitis media: 50 mg/kg IM in single dose; Maximum dose: 1 gm/day
Meningitis: 100 mg/kg IV or IM in single daily dose or (or in equally divided doses twice a day); Maximum dose: 4 gm/day
Duration of therapy: Continue for more than 2 days after signs and symptoms of infection have disappeared. Usual duration is 4 to 14 days; in complicated infections, longer therapy may be required.
Preparation:
Temtrix is supplied as a sterile crystalline powder in glass vial.
Temtrix 1gm IM Injection: Blister Pack of 1 vial containing 1gm Ceftriaxone (as Sterile Ceftriaxone Sodium USP) accompanied by one ampoule of 3.5 ml Lidocaine 1% BP injection.
Temtrix 1gm IV Injection: Blister Pack of 1 vial containing 1gm Ceftriaxone (as Sterile Ceftriaxone Sodium USP) accompanied by one ampoule of 10 ml Water For Injection BP
Temtrix 2 gm IV Injection: Blister Pack of 1 vial containing 2 gm Ceftriaxone (as Sterile Ceftriaxone Sodium USP) accompanied by two ampoules of 10 ml Water for Injection BP.